SpoilerTV has the short synopsis for Chuck episode 5.10, “Chuck vs. Bo”, which airs Friday, January 13 at 8/7c on NBC.
Chuck and Sarah must go to Vail on one last mission, where they get some help from Bo Derek; Jeff and Lester continue their mission.
So Chuck and Sarah are going on a final mission, and Jeff and Lester are continuing a mission of their own. I wonder…could the endgame have Jeff and Lester becoming spies under the guise of touring with JEFFSTER? Or is that too outlandish?